Congratulations Laleh

Laleh Haghverdi won the Peter and Traudl Engelhorn Foundation research prize 2018 on the topic “Computational Biology: New Methods in Biology-Oriented Information Technologies with Impact on Basic Research and Application” for her contributions to development of computational tools for understanding and analysis of single-cell transcriptomics data.

Single-cell measurement technologies have been increasingly in use over the past years for investigation of heterogeneities among cells (e.g. in tumors) or transient cell states as in development and cell differentiation. The new single-cell measurement techniques pose new computational challenges for analysis and interpretation of the collected data.

Laleh has contributed to pioneering research on cell lineage tree analysis and development of data integration methods for single-cell data. Her proposed computational strategy for analysis of continuous cell lineage trajectories based on diffusion maps is being used by several researchers today and her contribution to single-cell transcriptomics data integration by mutual nearest neighbors (MNN) matching in high dimensions has proven effective for accelerated achievement to the goals of large scale single-cell projects such as the Human Cell Atlas (HCA), where integrating several data sets collected at several laboratories using different technologies is a necessity.

Welcome Cécile Le Sueur

Cécile is a master student in Computational Science at EPFL (Switzerland). She joined the Huber group for an internship in August 2017 and will work with Dorothee and Arne on proteomics data to study drug (off-)targets and systems-wide effects of drug treatment.

Welcome Frederik Ziebell

Frederik has a PhD in Applied Mathematics from Heidelberg University and the German Cancer Research Center (DKFZ). He works on developing statistical methods for high-dimensional heterogeneous data and the analysis of multi-omic level drug treatment effects in collaboration with Cellzome.

Welcome Almut Lütge

Almut is a master student in molecular biotechnology at the University of Heidelberg. She joined the Huber group in 2017 and works on the analysis of RNA-seq data from Chronic lymphatic leukemia (CLL) samples.

Welcome Arne Smits

Arne has a PhD degree from the Radboud University (Nijmegen, The Netherlands). His previous research in the laboratory of Prof. Michiel Vermeulen focused on the identification and quantification of protein-protein and DNA-protein interactions using quantitative proteomics. As a EIPOD postdoctoral fellow at EMBL, he is studying the systems-wide effects of drug treatment in collaboration with Cellzome and the Steinmetz group.

Congratulations Sophie Rabe

Sophie studied Molecular Biotechnology at the University of Heidelberg. She joined the Huber Group in Spring 2014 as student research assistant and worked on genomic biomarkers of drug sensitivity in primary blood cancer cells. For her PhD thesis, Sophie is now joining the group of Sascha Dietrich at NCT Heidelberg, where she will work on the SYMPATHY project, an integrated system medicine approach to personalized and targeted therapy in leukaemia and lymphoma. This multidisciplinary project is intended to have direct clinical impact on patient care in blood cancers.

Welcome Karsten Bach

Karsten Bach has a B.Sc. in Biology from the University of Bonn. He joined the Huber group in March 2016. At EMBL, he is finishing up his M.Sc. in Molecular Biotechnology and working on quantitative proteomics together with Dorothee Childs and Nikos Ignatiadis.